Manuscript for Review Process
Preparation And Characterization Of Fe(Ii), Ni(Ii) And Cu(Ii) Complexes Of Metronidazole
Abstract:
1-(2-hydroxylethyl)-2-methyl-5-nitroimidazole complexes of Fe(II), Ni(II) and Cu(II), were prepared in methanol. The complexes were characterized using melting point, infrared, uv/visible spectroscopy The increase in the melting point of the complexes compared to the free ligand provided evidence for complexation. The 1-(2-hydroxylethyl)-2-methyl-5-nitroimidazole is a bidentate ligand, which coordinated to the Fe(II), Cu(II) and Ni(II) ions through the oxygen of the hydroxyl group and nitrogen of -C=N group giving the complexes of the form M(met)2(M= Cu) and M(met)2.2H2O (M=Fe and Ni).It is found that Fe(II) and Ni(II) formed complexes of octahedral geometry, while Cu(II) formed complexes of square planar geometry , due to the nature and steric disposition of the metronidazole molecule.
Keywords:
Metronidazole-complexes, ligand
