Name: Dr. Anwar Ullah
Educational Qualification: B.Sc., M.Sc., Ph.D. (Brazil), Postdoc (Brazil).
Designation: Assistant Professor
Department: Chemistry, Biochemistry, Biomolecular Crystallography
University: COMSATS University Islamabad
Email: anwar.ms90@yahoo.com
Research Interests: Biochemistry, Structural and Molecular Biology, Cloning, Expression, Purification, characterization, and crystallization of proteins both from natural and recombinant sources, structure determination, Protein crystallography, structure-based drug discovery, protein-protein and protein-ligand interaction, structure bioinformatics, crystal diffraction, data collection, data processing, and structural solution.
Biography: Dr. Anwar Ullah is a full-time Assistant Professor in Biosciences and working in the area of Biochemistry, structural and Moleculecular Biology. Expertise and research interests Purification, characterization, and crystallization of proteins from both natural and recombinant sources, Protein crystallography, structure determination, structure base drug discovery, protein-protein and protein-ligand interaction, structure bioinformatics, crystal diffraction, data collection, data processing, and structural solution.
Additional credits:
Fellowships awarded:
Languages:
Potential reviewer of the journals:
Total number of articles published: 30
First author: 15
Corresponding author: 03
1) Thrombin-like enzymes from snake venom: Structural characterization and mechanism of action.
Ullah, A. Masood R, Ali I, Ullah K, Ali H, Akbar H, Betzel C, Int. J. Biol. Macromol. Mar 28; 114:788-811. IF: 3.67
2) Spider's Venom Phospholipases D: A structural review.
Masood R, Ullah K, Ali H, Ali I, Betzel C, Ullah A. Int. J. Biol. Macromol. Volume 107, Part A, Feb. 2018, Pages 1054-1065. IF: 3.67
3) Evaluation of antidiabetic potential of steroidal alkaloid of Sarcococca saligna.
Ullah Jan N, Ali A, Ahmad B, Iqbal N, Adhikari A, Inayat-Ur-Rehman, Ali A, Ali S, Jahan A, Ali H, Ali I, Ullah A, Musharraf SG. Biomed. Pharmacother. 2018 Feb. 15; 100:461-466. IF: 2.60
4) Synthesis, structural characterization and catalytic application of citrate-stabilized monometallic and bimetallic palladium@copper nanoparticles in microbial anti-activities. Ullah, I.; Khan, K.; Sohail, M. Ullah, K., Ullah A. International Journal of Nanomedicine, 2017 Dec.; 12, 8735-8747. IF: 4.30
5) Ac2-26 peptide and serine protease of Bothrops atrox similarly induces angiogenesis without triggering local and systemic inflammation in a murine model of dorsal skinfold chamber.
Molás RB, de Paula-Silva M, Masood R, Ullah A, Gimenes AD, Oliani SM. Toxicon. 2017 Oct.; 137:7-14. IF: 2.50
6) Potential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase-D.
Chaves-Moreira D, de Moraes FR, Caruso ÍP, Chaim OM, Senff-Ribeiro A, Ullah A, da Silva LS, Chahine J, Arni RK, Veiga SS. J. Cell. Biochem. 2017Apr. 07 118(4):726-738. IF: 3.25
7) Serine proteinases from Bothrops atrox and Bothrops brazili facilitate angiogenesis upon inducing PI3K/Akt signaling axis.
Bhat SK, Joshi MB, Ullah A, Masood R, Biligiri, SG, Arni RK, Satyamoorthy, K., Toxicon, Dec 1.2016.124:63-72. IF: 2.50
8) Tyrosine binding and promiscuity in the arginine repressor from the pathogenic bacterium Corynebacterium pseudotuberculosis.
Mariutti RB, Ullah A, Araujo GC, Murakami MT, Arni RK. Biochem. Biophys. Res. Commun. 2016 Jul 8; 475(4):350-5. IF: 2.41
9) Functional Expression, Monodispersity and Conformational Changes in the SBMV virus viral VPg on binding TFE.
Mariutti RB, Caruso IP, Ullah A, De Morais FR, Rehders D, Arni RK. Int. J. Biol. Macromol. 2015 (15); 30118-5. IF: 2.86
10) Crystal structure of mature 2S albumin from Moringa oleifera seeds.
Ullah A, Mariutti RB, Masood R, Caruso IP, Gravatim Costa GH, Millena de Freita C, Santos CR, Zanphorlin LM, Rossini Mutton MJ, Murakami MT, Arni RK. Biochem. Biophys. Res. Commun.2015 (15)30787-7. IF: 2.41
11) Crystal structure of Staphylococcus aureus exfoliative toxin D-like protein: Structural basis for the high specificity of exfoliative toxins.
Mariutti RB, Souza TA, Ullah A, Caruso IP, de Moraes FR, Zanphorlin LM, Tartaglia NR, Seyffert N, Azevedo VA, Le Loir Y, Murakami MT, Arni RK. Biochem. Biophys. Res. Commun. 2015 467(1):171-7. IF: 2.41
12) Ac2-26 Mimetic Peptide of Annexin A1 Inhibits Local and Systemic Inflammatory Processes Induced by Bothrops moojeni Venom and the Lys-49 Phospholipase A2 in a Rat Model.
Stuqui B, de Paula-Silva M, Carlos CP, Ullah A, Arni RK, Gil CD, Oliani SM. PLoS One. 2015; 10(7):e0130803. IF: 3.32
13) Preparation and Characterization of Monomodal Grapevine Virus A Capsid Protein.
Santana VS, Mariutti RB, Eberle RJ, Ullah A, Caruso IP, Arni RK. Protein Pept.Lett. 2015; 22(8):712-8. IF: 1.01
14) Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D.
Coronado MA, Ullah A, da Silva LS, Chaves-Moreira D, Vuitika L, Chaim OM, Veiga SS, Chahine J, Murakami MT, Arni RK. Curr. Protein Pept. Sci. 2015; 16(8):768-74. IF: 3.15
15) Crystallization and preliminary X-ray diffraction studies of an L-amino-acid oxidase from Lachesis muta venom.
Ullah A, Masood R, Spencer PJ, Murakami MT, Arni RK. Acta Crystallogr. F Struct. Biol. Commun. 2014 70(Pt.11):1556-9. IF: 0.54
16) Crystallization and preliminary X-ray diffraction analysis of a novel sphingomyelinase D from Loxosceles gaucho venom.
Ullah A, Magalhães GS, Masood R, Mariutti RB, Coronado MA, Murakami MT, Barbaro KC, Arni RK. Acta Crystallogr. F Struct. Biol. Commun. 2014 70 (Pt 10):1418-20. IF: 0.54
17) Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins.
Gremski LH, Trevisan-Silva D, Ferrer VP, Matsubara FH, Meissner GO, Wille AC, Vuitika L, Dias-Lopes C, Ullah A, de Moraes FR, Chávez-Olórtegui C, Barbaro KC, Murakami MT, Arni RK, Senff-Ribeiro A, Chaim OM, Veiga SS. Toxicon. 2014 83: 91-120. IF: 2.50
18) Rapid purification of serine proteinases from Bothrops alternatus and Bothrops moojeni venoms.
Fernandes de Oliveira LM, Ullah A, Masood R, Zelanis A, Spencer PJ, Serrano SM, Arni RK. Toxicon. 2013, 76: 282-90. IF: 2.50
19) Crystal structure of Jararacussin-I: the highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes.
Ullah A, Souza TA, Zanphorlin LM, Mariutti RB, Santana VS, Murakami MT, Arni RK. Protein Sci. 2013 22(1):128-32. IF: 2.86
20) Purification, crystallization and preliminary X-ray diffraction analysis of a class P-III metalloproteinase (BmMP-III) from the venom of Bothrops moojeni.
Ullah A, de Souza Tde A, Masood R, Murakami MT, Arni RK. Acta Crystallogr. Sect F Struct. Biol. Cryst. Commun. 2012 68(Pt. 10):1222-5. IF: 0.54
21) Purification, crystallization and preliminary X-ray diffraction analysis of crotamine, a myotoxic polypeptide from the Brazilian snake Crotalus durissus terrificus.
Coronado MA, Georgieva D, Buck F, Gabdoulkhakov AH, Ullah A, Spencer PJ, Arni RK, Betzel C. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 201268(Pt. 9):1052-4. IF: 0.54
22) Crystallographic portrayal of different conformational states of a Lys49 phospholipase A? homologue: insights into structural determinants for myotoxicity and dimeric configuration.
Ullah A, Souza TA, Betzel C, Murakami MT, Arni RK. Int. J. Biol. Macromol. 2012 51 (3): 209-14. IF: 2.60
23) Structural insights into selectivity and cofactor binding in snake venom L-amino acid oxidases.
Ullah A, Souza TA, Abrego JR, Betzel C, Murakami MT, Arni RK. Biochem. Biophys. Res. Commun. 2012 421(1):124-8. IF: 2.41
24) Crystallization and preliminary X-ray diffraction analysis of an L-amino-acid oxidase from Bothrops jararacussu venom.
Ullah A, Coronado M, Murakami MT, Betzel C, Arni RK. Acta Crystallogr.Sect. F Struct. Biol. Cryst. Commun. 2012 68(Pt. 2):211-3. IF: 0.54
25) Structure of a novel class II phospholipase D: catalytic cleft is modified by a disulphide bridge.
de Giuseppe PO, Ullah A, Silva DT, Gremski LH, Wille AC, Chaves Moreira D, Ribeiro AS, Chaim OM, Murakami MT, Veiga SS, Arni RK. Biochem. Biophys. Res. Commun. 2011 409(4):622-7. IF: 2.41
26) Crystallization and preliminary X-ray diffraction analysis of a class II phospholipase D from Loxosceles intermedia venom.
Ullah A, de Giuseppe PO, Murakami MT, Trevisan-Silva D, Wille AC, Chaves-Moreira D, Gremski LH, da Silveira RB, Sennf-Ribeiro A, Chaim OM, Veiga SS, Arni RK. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2011 67(Pt. 2):234-6. IF: 0.54
27) Removal of Methylene Blue Dye from Aqueous Solution by Using Powdered Saccharum Arundinaceum Leaves. Muhammad Ullah, Khakemin Khan, Rasool Kamal, Muhammad Sohail, Abid Ullah, Kifayat Ullah, Anwar Ullah, Shabnum Shaheen, Inayat Ullah, Zafar Ali Shah, Transylvanian Review, 2017 Vol. XXV, No. 18. 4746-4752. IF: 0.048
28) Glycosylation in Snake Venom Proteinases.
Monika Coronado, Raphael J. Eberle, Anwar Ullah, Raghuvir K Arni. Toxicon. Submitted, Jan 02, 2018. IF: 2.50
29) Exploring the Binding Mechanism of Flavonoid Quercetin to Phospholipase A2: Fluorescence Spectroscopy and Computational Approach.
Reetesh Kumar, Ícaro P Caruso, Anwar Ullah, Marinonio Lopes Cornélio, Marcelo Andres Fossey, Fátima Pereira de Souza, Raghuvir Krishnaswamy Arni. European Journal of Experimental Biology, 2007, Vol.7 No.5:33.
Book chapters:
? Structural Biology of Toxins; Three-dimensional Structures and Mechanisms of Snake Venom Serine Proteinases, Metalloproteinases and Phospholipase A2s. M. A. Coronado, F. R. de Moraes, A. Ullah, R. Masood, V.S. Santana, R. Mariutti, H. Brognaro, D. Georgieva, M.T. Murakami C. Betzel and R. K. Arni. Toxinology, 2014, pp. 1-25.
? Determining the structures of the snake and spider toxins by X-rays Anwar Ullah, Rehana Masood, Zafar Hayat, Ahmed Hafeez, Springer Protocols, 2018.
Serial no:IIEBM0495