Name: Dr. Jane Ru Choi
Educational Qualification: B.S. Biomedical Science (Honours) M.S. (Engineering Science) Ph.D. (Biomedical Engineering), Postdoc
Designation: Postdoctoral Research Fellow, The University of British Columbia, Canada.
Department: Health Research
University: University of British Columbia
Email: janeruchoi@gmail.com
Research Interests: Point-of-care (POC) technologies, Stem cell technologies, Single cell analysis, Food technologies.
Biography:
AWARDS AND HONORS
2018-2021 - Michael Smith Foundation for Health Research Postdoctoral Fellowship (Top 20%)
2017 - Mitacs Postdoctoral Fellowship
2015-2016 - Bioinspired Engineering and Biomechanics Center Research Award (Top 5%)
2015-2016 - Postgraduate Research Grant (PPP), University of Malaya
2013-2016 - High Impact Research Brightspark, University of Malaya (Top 10%)
2012-2016 - Chak Kai Koong Association National Academic Award (Top 10%)
2012-2016 - National Cooperation Organization Academic Award (Top 10%)
2012-2016 - High Impact Research and Postgraduate Research Fellowship
2012-2016 - Graduate Research Assistantship Scheme, University of Malaya
2012 - Final Year Project Presentation Award, UKM (Top 20%)
2008-2012 - Public Service Department of Malaysia Academic Award (JPA), Malaysia
2008-2012 - Dean List Awards (UKM), Malaysia (Top10%)
PROFESSIONAL AFFILIATIONS
Membership of
• American Chemical Society (ACS)
• Institute of Food Technologies (IFT)
• British Columbia Food Technologies (BCFT)
• UBC Postdoctoral Association (UBC PDA)
• SelectBIO
• Tissue Engineering and Regenerative Society of Malaysia (TESMA)
1. J. R. Choi, B. Pingguan-Murphy, W. A. B. Wan Abas, M. A., Noor Azmi, S. Z. Omar, K.H. Chua & W. K.
Z. Wan Safwani (2014). Hypoxia promotes growth and viability of human adipose-derived stem cells with
increased growth factors secretion. Journal of Asian Scientific Research, 4(7), 328-338.
2. J. R. Choi, B. Pingguan-Murphy, W. A. B. Wan Abas, M. A. Noor Azmi, S. Z. Omar, M. A., K.H. Chua &
W. K. Z. Wan Safwani (2014). Impact of low oxygen tension on stemness, proliferation and differentiation
potential of human adipose-derived stem cells. Biochemical and Biophysical Research Communications,
448(2), 218-224. (IF: 2.559)
3. J. R. Choi, B. Pingguan-Murphy, F. Xu, W. A. B. Wan Abas, K.W. Yong, C. T. Poon, M. A. Noor Azmi, S.
Z. Omar, K.H. Chua & W. K. Z. Wan Safwani (2015). In Situ Normoxia Enhances Survival and Proliferation
Rate of Human Adipose Tissue-Derived Stromal Cells without Increasing the Risk of Tumourigenesis. PLoS
One, 10(1), e0115034. (IF: 2.766)
4. J. R. Choi, R. Tang, S. Wang, W. A. B. W. Abas, B. Pingguan-Murphy & F. Xu (2015). Paper-based
Sample-to-Answer Molecular Diagnostic Platform for Point-of-Care Diagnostics. Biosensors and
Bioelectronics, 74,427-439. (IF: 8.173)
5. J. R. Choi, J. Hu, S Feng, W. A. B. W. Abas, B. Pingguan-Murphy, F. Xu (2016). Sensitive Biomolecule
Detection in Lateral Flow Assay with A Portable Temperature-Humidity Control Device. Biosensors and
Bioelectronics, 79, 98-107. (Featured in Elsevier’s summer chemistry collection, one of the 25 most
downloaded articles from Biosensors and Bioelectronics) (IF: 8.173)
6. J. R. Choi, J. Hu, R. Tang, Y. Gong, S. Feng, H. Ren, T. Wen, X. Li, W. A. B. W. Abas, B. Pingguan-
Murphy & F. Xu (2016). An Integrated Paper-based Sample-to-Answer Biosensor for Nucleic Acid Testing at
the Point of Care. Lab on a Chip, 16 (3), 611 – 621. (ESI Highly Cited Paper, 2016 Top 25 Lab on a Chip
Most Downloaded Articles, Featured in Chromatography collection) (IF: 5.995)
7. J. R. Choi, J. Hu, Y. Gong, S. Feng, W. A. B. W. Abas, B. Pingguan-Murphy & F. Xu (2016). An Integrated
Lateral Flow Assay for effective DNA amplification and detection at the Point of Care. Analyst, 141, 2930-
2939. (IF: 3.864)
8. J. R. Choi, Z. Liu, J. Hu, Y. Gong, S. Feng, W. A. B. W. Abas, H. Yang, Z. Qu, B. Pingguan-Murphy & F.
Xu (2016). Polydimethylsiloxane-Paper hybrid Lateral Flow Assay for Highly Sensitive Point-of-Care
Nucleic Acid Testing. Analytical Chemistry, 88 (12), 6254-6264 (Journal Cover) (IF: 6.042)
9. J. R. Choi, K. W. Yong, R. Tang, Y. Gong, W. Ting, H. Yang, A. Li, Y. C. Chia, B. Pingguan-Murphy & F.
Xu (2017). Lateral Flow Assay based on Paper-Hydrogel Hybrid Material for Sensitive Point-of-Care
Detection of Dengue Virus. Advanced Healthcare Materials. doi:10.1002/adhm.201600920. (Reported by
Materials Views/Advanced Science News: One Step Further towards Diagnosing Dengue at the Pointof-
Care, Materials Views China, X-MOL News, Editorial Highlight: Celebrating 5 years of Advanced
Healthcare Materials, Selected as Journal Cover) (IF: 5.609)
10. J. R. Choi, J. Hu, S.Q. Wang, W. A. B. W. Abas, B. Pingguan-Murphy, F. Xu (2017). Paper-based Point-of-
Care Testing for Diagnosis of Dengue Infections. Critical Reviews in Biotechnology, 37(1),100-111. (IF:
5.239)
11. J. R. Choi **, K. W. Yong & W. K. Z. Wan Safwani (2017). Effect of Hypoxia on Human Adipose-derived
Mesenchymal Stem Cells and its Potential Clinical Applications. Cellular and Molecular Life Sciences. 1-14.
(IF: 6.721)
12. J. R. Choi, K. W. Yong, R. Tang, Y. Gong, T. Wen, F. Li, B. Pingguan-Murphy, D. Bai & F. Xu (2017).
Advances and Challenges of Fully Integrated Paper-based Point-of-Care Nucleic Acid Testing. Trends in
Analytical Chemistry. 93,37-50. (IF: 7.034)
13. J. R. Choi **, K.W. Yong & J. Y. Choi (2017). Effects of Mechanical Loading on Human Mesenchymal
Stem Cells for Cartilage Tissue Engineering. Journal of Cellular Physiology. 9999, 1–16 (IF: 3.923)
14. J. R. Choi **(2017) Editorial: Human Adult Stem Cells: Their Biosafety and Current Status in Cell-based
Therapy (invited). Journal of Cell and Developmental Biology, 1 (4), 1-2.
15. J. R. Choi **, K.W. Yong, J. Y. Choi, A. Nilghaz, Y. Lin, J Xu & X. Lu (2018). Black Phosphorus and its
Biomedical Applications. Theranostics, 8(4),1005-1026. (IF: 8.537)
16. J. R. Choi, A. Nilghaz, L. Chen, K. Chou & X. Lu (2018). Modification of Thread-based Microfluidic
Device with Polysiloxanes for the Development of a Sensitive and Selective Immunoassay. Sensors and
Actuators B: Chemical. 260, 1043-1051. X-MOL News (IF: 5.667)
17. J. R. Choi **(2018). Editorial: Recent Advances in Single Cell Analysis (Invited). Journal of Cell and
Developmental Biology, 1 (2), 1-3.
18. J. R. Choi ** (2018). Biomaterials for Regenerative Medicine: Progress and Perspectives (Invited). Insights
in Regenerative Medicine. (In press)
19. K.W Yong*, J. R. Choi*, A. Saifullah & W.K.Z. Wan Safwani (2018). Biosafety and Bioefficacy
Assessment of Human Stem Cells: What Do We Know So Far? Regenerative Medicine 3.2, 219-232. (IF:
2.868)
20. K.W. Yong*, J. R. Choi*, M. Mohammadi, A., P. Mitha, A. Sanati-Nezhad & A. Sen (2018), Human Stem
Cell Therapy for Ischemic Tissues (Invited). Stem Cells International. (In press) (IF: 3.989)
21. W. K. Z. Wan Safwani, K.W. Yong, J. R. Choi, B. Pingguan-Murphy (2013). The effects of cryopreservation
on the biological efficacy of human adipose stromal cells: A Preliminary Study. Regenerative Research, 2 (2),
32-38.
22. K.W. Yong, B. Pingguan-Murphy, F. Xu, W. A. B. Wan Abas, J. R. Choi, S. Z. Omar, M. A. Noor Azmi,
K.H. Chua &. W. K. Z. Wan Safwani (2015). Phenotypic and Functional Characterization of Long-Term
Cryopreserved Human Adipose-derived Stem Cells. Scientific Reports, 5. (IF: 4.122)
23. K.W. Yong, W. K. Z. Wan Safwani, F. Xu, W. A. B. Wan Abas, J. R. Choi & B. Pingguan-Murphy (2015).
Cryopreservation of Human Mesenchymal Stem Cells for Clinical Applications: Current Methods and
Challenges. Biopreservation and Biobanking, 13(4),231-239. (IF: 1.827)
24. K.W. Yong, W. K. Z. Wan Safwani, F. Xu, X. Zhang, J. R. Choi, W. A. B. W. Abas, S. Z. Omar, M. A. Noor
Azmi, K.H. Chua, B. Pingguan-Murphy (2015). Assessment of Tumourigenic Potential in Long-Term
Cryopreserved Human Adipose-derived Stem Cells. Journal of Tissue Engineering and Regenerative
Medicine. doi: 10.1002/term.2120. (IF: 1.216)
25. Feng, S., J. R. Choi, T.J. Lu & F. Xu (2015). State-of-Art Advances in Liquid Penetration Theory and Flow
Control in Paper for Paper-based Diagnosis. Advances in Porous Flow, 5,16-29.
26. W. K. Z. Wan Safwani, C.W. Yong, K.W. Yong, J. R. Choi, M. A. Noor Azmi, S. Z. Omar, W. A. B. Wan
Abas, & B. Pingguan-Murphy (2015). The Effects of Hypoxia and Serum-free Conditions on the Stemness
Properties of Human Adipose-derived Stem Cells. Cytotechnology, 1-14. (IF: 1.461)
27. R. Tang, H. Yang, J. R. Choi, Y. Gong, S.S. Feng, B. Pingguan-Murphy, Q.S. Huang, J. Shia, Q Mei & F. Xu
(2016). Advances in Paper-Based Sample Pretreatment for Point-of-Care Testing. Critical Reviews in
Biotechnology. doi: 10.3109/07388551.2016.1164664. (IF: 5.239)
28. R. Tang, H. Yang, J. R. Choi, Y. Gong, J. Hu, S.S. Feng, B. Pingguan-Murphy, Q Mei & F. Xu (2016).
Improved Sensitivity of Lateral Flow Assay using Paper-based Sample Concentration Technique. Talanta,
152, 269-276. (IF: 4.244)
29. K. W. Yong, J. R. Choi & W. K. Z. Wan Safwani (2016). Biobanking of Human Mesenchymal Stem Cells:
Future Strategy to Facilitate Clinical Applications. Advances in Experimental Medicine and Biology. 951, 99-
110. (IF: 1.761)
30. X.Y. Cui, J. Hu, J. R. Choi, X. Wang, Y. Huang, T. Lu & F. Xu (2016). A Volumetric Meter Chip for Pointof-
Care Quantitative Detection of Bovine Catalase for Food Safety Control. Analytica Chimica Acta, 935,
207-212. (IF: 5.123)
31. J. Hu, J. R. Choi, S.Q. Wang, Y. Gong, S. Feng, B. Pingguan-Murphy, T.J. Lu & F. Xu (2017). Multiple Test
Zones for Improved Detection Performances in Lateral Flow Assay. Sensors and Actuators B: Chemical, 243,
484-488. (IF: 5.667)
32. L. Cao, X. Cui, J. Hu, Z. Li, J. R. Choi, Q. Yang, M. Lin, L.Y. Hui & F. Xu (2017). Advances in Digital
Polymerase Chain Reaction (PCR) and its Emerging Biomedical Applications. Biosensors and Bioelectronics.
90, 459-474. (IF: 8.173)
33. W. K. Z. Wan Safwani, J. R. Choi **, K.W. Yong, I, Ting., M. A. Noor Azmi, S. Z. Omar & B. Pingguan-
Murphy (2017). Hypoxia Enhances the Viability, Growth and Chondrogenic Potential of Cryopreserved
Human Adipose-derived Stem Cells. Cryobiology. 75, 91-99. (IF: 2.050)
34. R. Tang, H. Yang, Y. Gong, M. You, Z. Liu, J. R. Choi, T. Wen, Z. Qu, Q. Mei & F. Xu (2017). A Fully
Disposable and Integrated Paper-based Device for Nucleic Acid Extraction, Amplification and Detection. Lab
on a Chip. 17(7), 1270-1279. (Journal Cover) (IF: 5.995)
35. R. Tang, H. Yang, J. R. Choi , Y. Gong, J. Hu, T. W., X. L, B. X., Q Mei & F. Xu (2017). Paper-based
Device with on-Chip Reagent Storage for Rapid Extraction of DNA from Biological Samples. Microchimica
Acta. 1-10. (IF: 5.705)
36. Y. Gong, J. Hu, J. R. Choi, M. You, Y. Zheng, Xu B., T. Wen & F. Xu (2017). Improved Lateral Flow
Immunoassay for Highly Sensitive Detection of Brain Natriuretic Peptide at Point-of-Care. International
Journal of Nanomedicine. doi.org/10.2147/IJN.S135735. (IF: 4.370)
37. R. Tang, H. Yang, J. R. Choi, Y. Gong, M. You, T. Wen, A. Li, X Li, B. Xu, S. Z., Q. Mei & F. Xu (2017).
Capillary Blood-based Point-of-Care Diagnostics. Critical Reviews in Clinical Laboratory Sciences. 1-15.
doi: 10.1080/10408363.2017.1343796. (IF: 6.481)
38. L. Ma, A. Nilghaz, J. R. Choi, X. Liu & X. Lu (2018). Rapid Detection of Clenbuterol In Milk using
Microfluidic Paper-Based ELISA. Food Chemistry. DOI:10.1016/j.foodchem.2017.12.022 (IF: 4.946)
39. C-H T Yew, P. Azari, J. R. Choi, F. Li & B Pingguan-Murphy (2018). Electrospin-coating of Nitrocellulose
Membrane Enhances Sensitivity in Nucleic Acid-based Lateral Flow Assay. Analytica Chimica Acta 1009,
81-88 (IF: 5.123)
Serial no:IIEBM0462