Abstract:

Eight different Schiff base derivatives, N-(cinnamylidene)aniline (4a), N-(cinnamylidene)-4-bromoaniline (4b), N-(4-methoxycinnamylidene)aniline (4c), N-(4-methoxycinnamylidene)-4-fluoroaniline (4d), N-(4-methoxycinnamylidene)-3-chloroaniline (4e), N-(4-methoxycinnamylidene)-4-chloroaniline (4f), N-(4-methoxycinnamylidene)-2-bromoaniline (4g), and N-(4-methoxycinnamylidene)-4-bromoaniline (4h), were previously  synthesized from the corresponding cinnamaldehydes and anilines via microwave irradiation. ?n this study the prepared compounds were tested for their in vitro antibacterial activity. The disc diffusion method was used for the assessment of in vitro antibacterial activity compounds against Acinetobacter calcoaceticus strain and Pediococcus acidilactici.