Abstract:

Gastro-esophageal reflux disease (GERD) is an upper gastrointestinal tract disease that is characterized by various esophageal and extra-esophageal syndromes. Incidence and prevalence of GERD are increasing day by day due to poor dietary habits and lifestyles. Other pathological factors may include side effects associated with drugs, frequent transit LES relaxation, hypotensive LES, obesity, pregnancy and increased gastric volume and delayed emptying as well. PPIs are the most recommended method to treat GERD. Other may include H2 receptor blockers, antacid, surgery, long-term use of medications.