Abstract:

Inclusion in complex therapy of the drug Cocarnite allowed to prevent and to treat resulting hypoxia, to improve the condition of fetoplacental complex in pregnant women with AVO the conflict, which was manifested by a higher score on the Apgar scale, the absence of severe hypoxic lesions of the fetus. Summary. From dopplerometric data it was revealed that after a course of complex treatment with Cocarnite, the violation of uterine placental circulation decreased by 32.3%, of which the violation of the 1st uterine placental circulation decreased 1.4 times, the II degree 4.5 times compared with the group before treatment. There were no violations of uterine placental circulation in group after treatment by 32.3% more often than in the group before treatment. A statistically significant decrease in toxic products of the exchange of TZP, TRP, NPK and Opia proapoptical factor - cytochrome C in the blood serum when Cocarnitis is prescribed for complex treatment to pregnant women with ABO-conflict is pathogenetically justified. Decrease in serum TZP, TRP, NPK, OP, cytochrome C under the effect of treatment testifies to their importance in the pathogenesis of ABO-conflict in pregnant women with I (O) Rh (+) immunization, which is important to take into account in the monitoring of differential diagnosis of this disease.