Ana Rita Ramalho Figueiras

Ph.D. Thesis
Strategies to improve Omperazole Solubility and Permeability: The use of cyclodextrins and
mucoadhesive polymers in the buccal mucosa
Figueiras, A.
Trabalho apresentado para prestação de Provas de Doutoramento em Farmácia, na Especialidade de
Tecnologia Farmacêutica. Junho, 2009.
Books
Strategies to improve Omperazole Solubility and Permeability: The use of cyclodextrins and
mucoadhesive polymers in the buccal mucosa
Figueiras, A.; Veiga, F.
Editora: In Lambert Academic Publishing
Publicado em 2011.
ISBN: 978-3-8443-3192-9
Book Chapters
Oral Drug Delivery with Cyclodextrins;
Veiga, F.; Figueiras, A.; Vieira, A.;
In Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine: Current and Future Industrial
Applications;
Editor: E. Bilensoy, Wiley; Publicado em 2011;
ISBN: 978-0-470-47422-8.
Sistemas Mucoadesivos;
Figueiras, A.; Varum, F.; Veiga, F.;
In Novas Formas Farmacêuticas para Administração de Fármacos;Edição Fernando Pessoa; Publicado em 2012;
ISBN: 978-989-643-078-8.
Libertação Modificada por Inclusão do Fármaco em Ciclodextrinas;
Veiga, F.; Figueiras, A.;
In Novas Formas Farmacêuticas para Administração de Fármacos;
Edição Fernando Pessoa; Publicado em 2012;
ISBN: 978-989-643-078-8.
Polyplexes as Nanovectors for Gene Therapy;
Pereira, P.; Sousa, F.; Figueiras, A.;
In Multi Volume Set on Recent Development in Biotechnology;
Milk Proteins: Drug Delivery Systems;
Ribeiro, A; Veiga, F.; Figueiras, A.;
In Encyclopedia Biomedical Polymers and Polymeric Biomaterials;
DOI: 10.1081/E-EBPP-120050396
Biodegradable Polymeric Nanostructures: Design and Advances in Oral Delivery for
Neurodegenerative Disorders;
Andreza Maria Ribeiro, Francisco Veiga, Ana Figueiras
In: Nanostructures in therapeutic medicine, volume 1: Nanostructures for Oral Medicine
Editor: Elsevier
Accepted for publication in January 2017
International Articles with Peer-Review
Interaction of Omeprazole with a Methylated Derivative of ß-cyclodextrin: Phase solubility, NMR
Spectroscopy and Molecular Simulation;
Figueiras, A.; Sarraguça, J.M.G.; Carvalho, R.A.; Pais, A.A.C.C.; Veiga, F.;
Pharmaceutical Research; (2007) 24: 377-389;
DOI: 10.1007/s11095-006-9161-8
Solid-state characterization and dissolution profiles of the inclusion complexes of omeprazole with
native and chemically modified ß-cyclodextrin;
Figueiras, A.; Carvalho, R.A.; Ribeiro, L.; Torres-Labandeira, J.J.; Veiga, F.;
European Journal of Pharmaceutics and Biopharmaceutis; (2007) 67: 531-539;
DOI: 10.1016/j.ejpb.2007.03.005
Preparation and physicochemical characterization of inclusion complex between omeprazole :
methyl-beta-cyclodextrin in solid state;
Figueiras, A.; Ribeiro, L.; Vieira, M.T.; Veiga, F.;
Journal of Inclusion Phenomena and Macrocyclic Chemistry; (2007) 57: 173-177;
DOI: 10.1007/s10847-006-9200-4
New insight into the discrimination between omeprazole enantiomers by cyclodextrins in aqueous
solution;
Figueiras, A.; Sarraguça, J.M.G.; Pais, A.A.C.C.; Veiga, J.F.; Carvalho, R.A.;
Journal of Inclusion Phenomena and Macrocyclic Chemistry; (2008) 62: 345-351;
DOI: 10.1007/s10847-008-9477-6
Preparation and solid-state characterization of inclusion complexes formed between miconazole and
methyl-ß-cyclodextrin;
Ribeiro, A.; Figueiras, A.; Veiga, F.; Santos, D.;
AAPSPharmSciTechn; (2008) 9: 1102-1109;
DOI: 10.1208/s12249-008-9143-8
In vitro evaluation of natural and methylated cyclodextrins as buccal permeation enhancing system
for omeprazole delivery;
Figueiras, A.; Hombach, J.; Veiga, F.; Bernkop-Schnürch, A.;
European Journal of Pharmaceutics and Biopharmaceutis; (2009) 71: 339-345;
DOI: 10.1016/j.ejpb.2008.08.016
Combining strategies to optimize a gel formulation containing miconazole: the influence of modified
cyclodextrin on textural properties and drug release;
Ribeiro, A.; Figueiras, A.; Freire, C.; Santos, D.; Veiga, F.;
Drug Development and Industrial Pharmacy; (2010) 36: 705-714;
DOI: 10.3109/03639040903452260
The role of L-arginine in inclusion complexes of omeprazole with cyclodextrins;
Figueiras, A.; Sarraguça, J.M.; Pais, A.A.; Carvalho, R.A.; Veiga, F.;
AAPSPharmSciTech; (2010) 11: 233-240;
DOI: 10.1208/s12249-009-9375-2
A comprehensive development strategy in buccal drug delivery;
Figueiras, A.; Pais, A.A.; Veiga, F.;
AAPSPharmSciTech; (2010) 11: 1703-1712;
DOI: 10.1208/s12249-010-9546-1
Characterization of polyplexes involving small RNA;
Pereira, P.; Jorge, A.F.; Martins, R.; Pais, A.A.C.C.; Sousa, F.; Figueiras, A.;
Journal of Colloid and Interface Science (2012) 387: 84-94;
DOI: 10.1016/j.jcis.2012.07.088
The systems containing clays and clay minerals from modified drug release: A review;
Rodrigues, L.A.S.; Figueiras, A.; Veiga, F.; Freitas, R.M.; Silva Filho, E.C.; Nunes, L.C.; Leite,
C.M.S.;
Colloids and Surfaces B – Biointerfaces (2013) 103: 642-651;
DOI: 10.1016/j.colsurfb.2012.10.068
Microwave synthesis and in vitro stability of diclofenac-ß-cyclodextrin conjugate for colon delivery;
Vieira, A.C.F.; Serra, A.C.; Carvalho, R.A.; Gonsalves, A.; Figueiras, A.; Veiga, F.J.; Basit, A.W.;
Gonsalves, M. d’A.R.;
Carbohydrate Polymers (2013) 93: 512-517;
DOI: 10.1016/j.carbpol.2012.12.053
Strategies to increase stilbene solubility and stability: a comparative study between cyclodextrins and
bile acids;
Silva, F.; Figueiras, A.; Gallardo, E.; Nerín, C.; Domingues, F.C.;
Food Chemistry (2014) 145: 115-125;
DOI: 10.1016/j.foodchem.2013.08.034
Purification of pre-miR-29 by arginine-affinity chromatography;
Pereira, P.; Sousa, A.; Queiroz, J.; Correia, I.; Figueiras, A.; Sousa, F.;
Journal of Chromatography B (2014) 951-952: 16-23;
http://dx.doi.org/10.1016/j.jchromb.2014.01.020
New approach for purification of pre-miR-29 using lysine-affinity chromatography;
Pereira, P.; Sousa, A.; Queiroz, J.; Figueiras, A.; Sousa, F.;
Journal of Chromatography A (2014) 1331: 129-132;
http://dx.doi.org/10.1016/j.chroma.2014.01.033
Preparation of Supramolecular Hydrogels Containing Poloxamers and Methyl-ß-cyclodextrin;
Garcia, M.J.; Ruivo, J.; Oliveira, R.; Figueiras, A.;
Letters in Drug Design & Discovery (2014); 11,
DOI:10.2174/1570180811666140220005117
Supramolecular gels of poly-a-cyclodextrin and PEO-based copolymers for controlled drug release;
Susana, M.N. Simões; Francisco Veiga; Ana C. F. Ribeiro; Ana R. Figueiras; Pablo Taboada; Angel
Concheiro; Carmen Alvarez-Lorenzo;
European Journal of Pharmaceutics and Biopharmaceutis (2014), 87,
DOI:10.1016/j.ejpb.2014.04.006
Polymeric micelles for oral drug administration enabling locoregional and systemic treatments.
Susana MN Simões, Ana R Figueiras, Francisco Veiga, Angel Concheiro, Carmen Alvarez-Lorenzo
Expert Opinion on Drug Delivery 2014; 12:1-22.
DOI:10.1517/17425247.2015.960841
Pharmaceutical-grade pre-miR-29 purification using an agmatine monolithic support.
Patrícia Pereira, Ângela Sousa, João A. Queiroz, Ana Figueiras, Fani Sousa
Journal of Chromatography A 2014; 1368:173-182.
DOI:10.1016/j.chroma.2014.09.080
Molecular interaction governing solubility and release profiles in supramolecular systems containing
fenbufen, pluronics and cyclodextrins.
Ana Figueiras, Sandra C. C. Nunes, Susana Simões, Alberto A. C. C. Pais, Francisco Veiga
Journal of Inclusion Phenomena and Macrocyclic Chemistry 2015; 81. DOI:10.1007/s10847-014-
0466-7
Resveratrol encapsulation with methyl-β-cyclodextrin for antibacterial and antioxidant delivery
applications.
Andreia Duarte, Ana Martinho, Ângelo Luís, Ana Figueiras, Mónica Oleastro, Fernanda C.
Domingues, Filomena Silva
LWT- FoodScience and Technology. 04/2015; 63:1254-1260. DOI:10.1016/j.lwt.2015.04.004
The main potentialities of resveratrol for drug delivery systems.
Joana Ruivo, Cátia Francisco, Rita Oliveira, Ana Figueiras:
Brazilian Journal of Pharmaceutical Sciences. 2015; 51(3).
DOI:10.1590/S1984-825020150003000
Improvements in topical ocular drug delivery systems: Hydrogels and contact lense.
A.M. Ribeiro, A. Figueiras, F. Veiga
Journal of Pharmacy and Pharmaceutical Sciences. 2015; 18:692-704
Analysis of pre-miR-29b binding conditions to amino acids by Surface Plasmon Resonance
Biosensor.
Patrícia Pereira, Carla Cruz, João António Queiroz, Ana Figueiras, Fani Sousa
Analytical methods. 2016; 8: 205-213
DOI:10.1039/C5AY02329G
Affinity approaches in RNAi-based therapeutics purification.
Patrícia Pereira, João A. Queiroz, Ana Figueiras, Fani Sousa
Journal of Chromatography. B, Analytical technologies in the biomedical and life sciences; 2016;
DOI:10.1016/j.jchromb.2016.01.022
Recombinant pre-miR-29b for Alzheimer´s disease therapeutics.
Patrícia A. Pereira, Joana F. Tomás, João A. Queiroz, Ana R. Figueiras, Fani Sousa
Scientific Reports; 2016; 6:19946.
DOI:10.1038/srep19946
Advances in time course extracelular production of human pre-miR-29b from Rhodovulum
sulfidophilum.
Pereira, P.; Pedro, A.Q.; Tomás, J.; Maia, C.J.; Queiroz, J.A.; Figueiras, A.; Sousa, F.
Applied Microbiology and Biotechnology 2016; 100:3723-34.
DOI: 10.1007/s00253-016-7350-x
Smart micelleplexes as a new therapeutic approach for RNA delivery.
Pereira, P.; Barreira, M.; Queiroz, J.A.; Veiga, F.; Sousa, F.; Figueiras, A.
Expert Opinion on Drug Delivery. 2016; 2:1-19
Current progress on microRNAs-based therapeutics in neurodegenerative diseases
Patrícia A. Pereira, João A. Queiroz, Ana R. Figueiras, Fani Sousa
WIREs RNA; Published Online: Nov 24, 2016
DOI: 10.1002/wrna.1409
New insights for therapeutic recombinant human miRNAs heterologous production: Rhodovolum
sulfidophilum vs Escherichia coli
Patrícia Pereira, Augusto Q. Pedro, João A. Queiroz, Ana R. Figueiras & Fani Sousa
Pages 1-8 | Received 03 Oct 2016, Accepted 17 Jan 2017, Published online: 10 Mar 2017
Bioengineered
Preparation and characterization of mixed polymeric micelles as a versatile strategy for meloxicam
oral administration
Amaral, A.; Magalhães, M.; Cabral, C.; Veiga, F.; Figueiras, A.
Letters in Drug Design & Discovery
Volume: 14
Year: 2017
DOI: 10.2174/1570180814666170505120728
National Articles with Peer-Review
Sistemas mucoadesivos de administração de fármacos na cavidade oral: mecanismo de mucoadesão e
polímeros mucoadesivos.
Figueiras, A.; Carvalho, R.; Veiga, F.
Rev. Lusófona de Ciências e Tecnologias da Saúde, 3(1), 2006, 87-102.
A mucosa bucal como via de administração alternativa de fármacos: potencialidades, limitações e
formas farmacêuticas.
Figueiras, A.; Carvalho, R.; Veiga, F.
Rev. Lusófona de Ciências e Tecnologias da Saúde, 4(2), 2007, 216-233.
A administração na mucosa bucal como uma estratégia alternativa à via oral.
Dias, S.; Figueiras, A.; Barata, P.; Oliveira, R.; Santos, D.; Veiga, F.
Rev. da Faculdade de Ciências da Saúde. 4, 2007, 118-133.
Evolução Terapêutica dos Sistemas de Libertação Modificada para Administração Oral
Nabais, I.; Veiga, F.; Figueiras, A.
Acta Farmacêutica Portuguesa, 2015, 4:101-133
Evaluation of host-guest complex formation between a benzimidazolic derivative and cyclodextrins
by UV-VIS spectrophotometry and differential scanning calorimetry;
Figueiras, A.; Ribeiro, L.; Torres-Labandeira, J.J.; Veiga, F.;
Journal of Inclusion Phenomena and Macrocyclic Chemistry; (2007) 57: 531-535;
DOI: 10.1007/s10847-006-9245-4