Email: anu.anu7@yahoo.com
Research Interests: Her current research focuses on studying the pathogenic role of TLRs, innate immune cells and heat shock proteins during chronic alcoholic liver disease. She is interested in identifying molecular targets and their specific targeting using nano-formulations as potential therapeutic candidate in alcoholic liver disease management.
Biography: She is working as a postdoctoral researcher at Department of Medicine, University of Massachusetts Medical school, USA. Her current research focuses on identifying molecular targets that plays critical role during alcohol-induced liver inflammation using a combination of primary cell culture and novel knock-out mouse models. She is evaluating the role of TLRs, heat shock proteins, ER chaperones, their inhibitors and nano-formulations as therapeutic targets in alcoholic liver disease. She is also testing anti-inflammatory efficacy of novel polymeric nanosystems specifically targeting liver macrophages. Previously, she worked as a research intern at Meharry Medical College, Nashville, TN, USA. She investigated anti-carcinogenic effects of endothelins and soy peptides in breast cancer. She received my Ph.D. from Department of Immunopathology at PGIMER (India) in December 2014. Her Ph.D. research work focused on evaluating the immunomodulatory potential of recombinant antigens of L. donovani in specific activation of macrophages. She showed that one of the antigens when used as an adjunct to the currently used drugs helped early parasite clearance at suboptimal doses of highly toxic chemotherapeutic drugs using experimental animal model and findings were published in an international journal.
Fellowships/Honors
- Senior Research Fellowship by Indian Council for Medical Research (ICMR), Govt. Of India, New Delhi, India during PhD study (Nov 2012-Oct 2014)
- Junior Research Fellowship by ICMR, Govt. Of India, New Delhi, India during PhD study (Nov 2009-Oct 2011)
- National Level PhD Entrance Test Qualifier conducted by Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India in July 2009
- University Gold Medal for securing top position in M.Sc. Examination (2008) at Patna University, Bihar, India
- Distinction in B.Sc. Examination (2006), Patna University, Bihar, India.
- American Association for the Study of Liver Diseases (AASLD)
- Indian Immunology Society, Lifetime member.
- Association of Basic Medical Scientists, PGIMER, Chandigarh, India, Lifetime member
- Editorial board member for journals-Acta Scientific Medical Sciences; Global Vaccines and Immunology; Journal of Cell Signaling and Damage-Associated Molecules
